About Dave Mascotti (Can you spot some of your favorite professors from about 2006?)
...a short history
I was born in a tiny town in the central part of Michigan's lower peninsula in 1964. (For an early photo of my very early athletic talents, click here.) In order to save me from having to re-explore all those pre-adolescent embarrassments, I'll skip ahead to my late teen years.  I grew up with an affinity for chemistry (medicinal synthetic, to be specific) and music (jazz trombone, to be specific).  By the time I was a senior at Reed City High School, I decided that I wanted to be a professional chemist and a part-time musician.  The reverse situation didn't seem a good choice because of the safety and legal issues of doing experiments at home.

To conserve money, my plan was to attend Ferris State College (now Ferris State University in Big Rapids, Michigan) for two years, then transfer to the University of Michigan for a degree in chemistry.  By a stroke of providence, my advisor at Ferris would have been my organic chemistry professor the following year.  He asked me if I was really serious about this chemistry career goal.  When I told him yes, he did several things (the details I still don't quite understand) that culminated in my late acceptance at Hope College in Holland, Michigan.  I had never been so challenged academically before in my life!  It turned out to be a great experience for me at Hope where I reconsidered my goal of becoming a medicinal chemist.  I realized that much of that type of work is organic synthesis and toxicology screening, which did not excite me in the way that I had hoped.  However, I did get excited about biochemistry because I thought that if we understood the biochemistry better, we could design drugs more rationally... (It turns out that I was just ahead of my time since that is now commonly done.)  So, I ended up working in Rod Boyer's laboratory characterizing novel enzyme activities for polyphenol oxidase, and earned a B.S. in chemistry.  I also got to play lead trombone in the Hope Jazz Ensemble for a few years and had the luxury of enjoying the beaches near Holland.

After visiting several graduate programs, I chose Texas A&M University in College Station, Texas, for work in the department of Biochemistry and Biophysics.  There, I worked in Tim Lohman's laboratory studying thermodynamic aspects of proteins and peptides binding to nucleic acids like DNA and RNA  About 4 years into my dissertation work, Tim took a position in the department of Biochemistry and Molecular Biophysics at the Medical School of Washington University in St. Louis.  I was invited to come along, which I did gladly.  While at Washington University, I met Bob Thach and we've collaborated ever since doing work on mechanisms of translational control of iron metabolism genes.  Also, while in St. Louis, I co-founded Code Blue which was/is an acoustic jazz group of approximately 5-8 people at any given time.  I also got to play (I can't thank them enough for being cool enough to let a hack like me sit in) with the group called ACO (who used to have a weekly gig at House of Swing and The Grog Shop), but I haven't played much in public since then.

In case yiou are interested in reading this kind of stuff, here's my full CV that describes my research and teaching background.

I also taught for two years in southern New Jersey as an assistant professor of chemistry at Stockton College where I taught general chemistry, biochemistry and jazz. I have now moved to Cleveland to take a position at John Carroll University. Here, I continue to teach biochemistry and chemistry, while also researching gene expression and protein-nucleic acid interactions.  Also, I served as the Chemistry Department Chair from 2005-2009. Currently, I expanded my repertoire into entrepreneurship by both teaching Intro to Entrepreneurship as well as serving in an advisory and collaborative capacity with various startup companies.

Dave's main page. Dave's e-mail.  


This page last updated on August 25, 2019

visitors since January 21, 2003.