Curriculum Vitae

David Paul Mascotti

January 6, 2024

lab: (216) 397-4216

fax: (216) 397-1791

e-mail: dmascotti@jcu.edu

Department of Chemistry

John Carroll University

1 John Carroll Blvd.

University Heights, OH 44118

Education

         Ph.D. in Biochemistry, 1992 Texas A&M University, College Station, TX

         B.S. in Chemistry, 1986 Hope College, Holland, MI 

Research and Teaching Positions

2010-present  Professor, John Carroll University, University Heights, OH

Interactions of Biological Molecules, Regulation of Gene Expression and Transfer

2004-2010 Associate Professor, John Carroll University, University Heights, OH

Interactions of Biological Molecules and Regulation of Gene Expression

 

2005-2009  Chair, Department of Chemistry, John Carroll University, University Heights, OH

 

1998-present  Assistant Professor, John Carroll University, University Heights, OH

 

Interactions of Biological Molecules and Regulation of Gene Expression

          1996-1998   Assistant Professor, Richard Stockton College, Pomona, NJ

Interactions of Biological Macromolecules         

 

 

1992-1996 Post-doctoral Research Associate, Washington University, St. Louis, MO

 

Mentor - Dr. Robert E. Thach

          Characterization of Factors Affecting Translation of Ferritin mRNA

         

1986-1992 Graduate Research Assistant, Texas A&M University, College Station, TX

 

Mentor - Dr. Timothy M. Lohman

          Thermodynamic Characterization of the Interaction of Positively Charged Peptides with Nucleic Acids

         

1985-1986 Independent Research, Hope College, Holland, MI

 

Mentor - Dr. Rodney F. Boyer 

          Characterization of the Ferroxidase Activities of Polyphenol Oxidase (Tyrosinase) and Ferritin from Phaseolus vulgaris

Certifications

2019 U.S. Department of Justice, National Institute of Justice Certificate in STR Data Analysis and Interpretation for Forensic Analysts

2019 U.S. Department of Justice, National Institute of Justice Certificate in Forensic DNA for Officers of the Court

Courses Taught

Biochemistry I, II, and III

General Biochemistry

Biochemistry Laboratory

General Chemistry I & II

General Chemistry Laboratory

Molecular Methods Laboratory

Informed Health Decisions

Jazz History & Analysis

Introduction to Entrepreneurship

Finance and Acconting for Entrepreneurs

Introduction to Pharmacy

First Year Seminar

Memberships

ACS

AAAS

Biophysical Society

CUR

Project Kaleidoscope

Sigma Xi

Honors, Awards & Grants         

2009-present Faculty Fellow in Entrepreneurship at JCU

2008-2012  Howard Hughes Medical Institute Undergraduate Science Education Program - Colleges 2008, $939,781 (denied)         

2004-2007  Nominated for a Henry Dreyfus Teacher-Scholar Award: "Interactions of the Antioxidant Protein, Manganese Superoxide Dismutase, with DNA," ($60,000) (denied)         

2004-2006 Henry Luce Foundation (co-author) Clare Booth Luce Award ($137,822) for two undergraduate scholarships         

Fall Semester 2003, Grauel Faculty Fellowship (Sabbatical) at John Carroll University         

2002 Heuer Award for Outstanding Achievement in Undergraduate Science Education (co-author) ($10,000)          

2001 NSF MRI Award for "Acquisition of ITC and DSC Calorimeters" ($97,378)          

2001 Henry Dreyfus Special Award in Chemistry (co-PI) for "Integration of Fluorescence Spectroscopy into Undergraduate Curriculum" ($20,000)         

2001 Inducted into Project Kaleidoscope (PKAL) Faculty for the 21st Century         

2000-2003 NSF REU Award (co-PI) for an "REU Site in Chemistry" ($137,061)          

2000 Nominated for a Henry Dreyfus Teacher-Scholar Award (denied)          

2000-2002 Henry Luce Foundation (co-author) Clare Booth Luce Award ($101,606) for two undergraduate scholarships          

1998-2002 Cottrell College Science Award (Sponsored by Bristol-Myers Squibb), $32,484          

1993-1996 National Institutes of Health (NIDDK) Post-Doctoral Fellowship          

1986-1987 Lechner Graduate Fellowship Texas A&M University          

1986 Sigma Xi Undergraduate Research Award Hope College, Holland, MI          

1983-1986 Almon T. & Harriet M. Godfrey Scholarship Hope College, Holland, MI

1982-1983 Michigan Competitive Academic Scholarship Ferris State College, Big Rapids, MI

84- April 2022, Annual A Celebration of Scholarship, John Carroll University,*Madison DeTullio and David Mascotti, "Purification and Evaluation of Manganese Superoxide Dismutase " (video presentation)

83- Glucosinolate accumulation in response to water availability in wildland mustard species. *Reicholf, R, Sanchez Alvarez, A, Matesanz, S, Mascotti, DP, Drenovsky, R, Botany 2021 Virtual Conference. (Poster P2PE005, abstract #627, July 20, 2021)

82- April 11, 2016, Annual A Celebration of Scholarship, John Carroll University,*Brandon Parr, Ellen Piccillo, David Mascotti, Esteban Celis, M.D . , Ph.D., Augusta University. , "Binding Properties of Peptide (RRWRRRRRRAAATAPDNLGYM) with Poly - IC" (poster)

81- October 19, 2012, Rustbelt RNA Meeting, Datyon,, Ohio, Katharine E. Stahon,* Stephanie Clack, Michael P. Martin & David P. Mascotti, "Kinetic Analysis of T7 RNA Polymerase from Novel DNA Templates " (poster)

80 - March 28, 2011, Tenth Annual A Celebration of Scholarship, John Carroll University, Stephanie Clack,* , Tanya Lahood, Oksana Kozlovskaya, Raymond Chahoud, Michael P. Martin & David P. Mascotti, "Comparison of Transcription using Short Single, Double, and Snapback DNA Templates" (poster)

79- March 28, 2011, Tenth Annual A Celebration of Scholarship, John Carroll University, Elizabeth Lewis,* , Ryan Schoonmaker & David P. Mascotti, "Interactions of Human Superoxide Dismutase 2 with RNA " (poster)

78- September 26, 2011, Rustbelt RNA Meeting, Dayton, Ohio, Stephanie Clack,* , Tanya Lahood, Oksana Kozlovskaya, Michael P. Martin & David P. Mascotti, "Comparison of Transcription using Short Single, Double, and Snapback DNA Templates" (poster)

77- September 26, 2011, Rustbelt RNA Meeting, Dayton,, Ohio, Elizabeth Lewis,* , Ryan Schoonmaker & David P. Mascotti, "Interactions of Human Superoxide Dismutase 2 with RNA " (poster)

76 - March 25, 2010, Ninth Annual A Celebration of Scholarship, John Carroll University, *James M. Hiznay,: Mark J. Waner & David P. Mascotti, Chemistry, “Fluorimetric Evidence for Structural Cooperativity in the Binding of Biotin to Streptavidin” (poster)

75 - March 25, 2009, Eighth Annual A Celebration of Scholarship, John Carroll University, *William E. Patton,: Mark J. Waner & David P. Mascotti, Chemistry, “Evidence for Structural Cooperativity in the Binding of Biotin by Streptavidin” (poster)

74 - March 25, 2009, Eighth Annual A Celebration of Scholarship, John Carroll University, *Emily Tillmaand, Lana Bengez, Iteen Cheng, & David P. Mascotti, Chemistry, "Nucleotide binding specificity of E. coli Manganese Superoxide Dismutase " (poster)

73 - March 25, 2009, Eighth Annual A Celebration of Scholarship, John Carroll University, *Iteen Cheng, Lana Bengez, & David P. Mascotti, Chemistry, “Thermodynamic Characterization of E. coli Manganese Superoxide Dismutase binding to single- and double-stranded polynucleic acids” (poster)

72 - October 17, 2008, Rustbelt RNA Meeting, Deer Creek, Ohio, Emily Tillmaand,* Lana Bengez,* Iteen Cheng,* & David P. Mascotti, "Nucleotide binding specificity of E. coli Manganese Superoxide Dismutase" (poster)

71 - March 13, 2008, Seventh Annual A Celebration of Scholarship, John Carroll University, Charles Ponyik*, Mark J. Waner and David P. Mascotti, "Is the Binding of Biotin to Streptavidin Cooperative?" (poster)

70 - March 13, 2008, Seventh Annual A Celebration of Scholarship, John Carroll University, Lana Bengex*, Iteen Cheng*, Angela Smolik and David P. Mascotti, "Thermodynamic Characterization of Manganese Superoxide Dismutase Binding to Single- and Double-stranded Nucleic Acids." (poster)

69 - March 13, 2008, Seventh Annual A Celebration of Scholarship, John Carroll University, Tania Lahood*, Michael P. Martin and David P. Mascotti, "Transcription Assays using Short Single, Double, and Hairpin Loop Templates." (poster)

68 - February 5, 2008, 52nd Annual Biophysical Society Meeting in Long Beach, CA, Ohio, Lana Bengez,* Iteen Cheng, Angela C. Smolik, & David P. Mascotti*, "Thermodynamic Characterization of Manganese Superoxide Dismutase Binding to Single- and Double-stranded Nucleic Acids." (poster)

67 - October 19, 2007, Rustbelt RNA Meeting, Deer Creek, Ohio, Lana Bengez,* Iteen Cheng,* Angela C. Smolik, & David P. Mascotti, "Thermodynamic Characterization of Manganese Superoxide Dismutase Binding to Single- and Double-stranded Nucleic Acids." (poster)

66 - October 21, 2006, Rustbelt RNA Meeting, Deer Creek, Ohio, Lana Bengez,* Angela C. Smolik, & David P. Mascotti, "Preferential Binding of Manganese Superoxide Dismutase to Single-stranded Nucleic Acids." (poster)

65 - March 22, 2006, Fifth Annual A Celebration of Scholarship, John Carroll University, Megan Mamolen* and David P. Mascotti, "siRNA" (poster)

64 - March 22, 2006, Fifth Annual A Celebration of Scholarship, John Carroll University, Robert J. Kall,* Michael Iannetti* and David P. Mascotti, "Effect of Ethanol as a Cosolvent on Charged Peptide Interactions with RNA." (poster)

63 - March 22, 2006, Fifth Annual A Celebration of Scholarship, John Carroll University, Mark J. Waner, Anthony Mustovich,* Seema Patel* and David P. Mascotti Intrinsic Tryptophan Fluorescence as a Structural Probe of the Streptavidin-Biotin System" (poster)

62 - October 28, 2005, Rustbelt RNA Meeting, Deer Creek, Ohio, Angela C. Smolik,* Stephanie C. Hovan, David P. Mascotti, "Interactions of MnSOD with Single Stranded RNA using Fluorescence Spectroscopy." (poster)

61 - October 28, 2005, Rustbelt RNA Meeting, Deer Creek, Ohio, David P. Mascotti,* Robert J. Kall, Michael P. Iannetti, "Effect of Ethanol as a Cosolvent on Charged Peptide Interactions with RNA." (poster) 

60 - March 16, 2005, University of Akron, Department of Chemistry, David P. Mascotti* "Reversibility of Thermal Denaturation of Streptavidin in the Presence of SDS" (invited seminar)

59 - March 16, 2005, Fourth Annual A Celebration of Scholarship, John Carroll University, Seema Patel,* Anthony Mustovich, David P. Mascotti and Mark J. Waner, “Binding of Urea to Streptavidin: Let's Get Specific!” (poster)

58 - March 16, 2005, Fourth Annual A Celebration of Scholarship, John Carroll University, Joshua D. Czerwinski,* Stephanie C. Hovan* and David P. Mascotti, “Quantitative Nonisotopic Nitrocellulose Filter Binding Assays: Bacterial Manganese Superoxide Dismutase-DNA Interactions.” (poster)

57 - March 16, 2005, Fourth Annual A Celebration of Scholarship, John Carroll University, Zachary Coleman,* David P. Mascotti, and Mark J. Waner, “ Streptavidin Stability under Different Denaturing Conditions ” (poster)

56 - March 16, 2005, Copernicus Therapeutics, Cleveland, OH, David P. Mascotti* "Interactions of Charged Peptides with Polynucleic Acids" (invited seminar)

55 - March 25, 2004, Third Annual A Celebration of Scholarship, John Carroll University, Joshua D. Czerwinski* and David P. Mascotti, “Chemiluminescent Nitrocellulose Filter Binding Assays: SOD/DNA Interaction as an Example.” (poster)

54 - March 17, 2004, ACS Meeting in Miniature, Cleveland Section, Joshua D. Czerwinski* and David P. Mascotti, " Chemiluminescent Nitrocellulose Filter Binding Assays: SOD/DNA Interaction as an Example. " (seminar)

53 - February 18, 2004, 48th Annual Biophysical Society Meeting in Baltimore, MD. Joshua D. Czerwinski* and David P. Mascotti presented a poster entitled " Chemiluminescent Nitrocellulose Filter Binding Assays: SOD/DNA Interaction as an Example ."

52 - October 31, 2003, Rustbelt RNA Meeting, Deer Creek Park (Ohio University Sponsor), I presented (Joshua Czerwinski* co-author) presented a poster entitled "Quantitative Non-Isotopic Nitrocellulose Filter Binding Assays:  Bacterial MnSOD-DNA Interactions"

51 - May 31, 2003, 35th Great Lakes Regional ACS Meeting, Loyola University in Chicago, Mark J. Waner (David P. Mascotti, co-author) presented "Reversibility of Thermal Denaturation of Streptavidin in the Presence of SDS. (seminar) 

50 - March 24, 2003, The 225th ACS National Meeting, New Orleans, LA, Rachel T. Finley (Saint Mary's College)* and David P. Mascotti presented "Determination of the equilibrium affinity for IRP1 binding IRE" (poster)

49 - March 24, 2003, The 225th ACS National Meeting, New Orleans, LA, David P. Mascotti and Michael P. Iannetti (Youngstown State University)* presented "Effect of Alcohol-containing Cosolvents on Charged Peptide Interactions" (poster)

48 - November 2, 2002, Rustbelt RNA Meeting, Deer Creek Park (Ohio University Sponsor), I presented (Rachel T. Finley* & Laureen M. Lenchak* co-authors) presented a seminar entitled "Thermodynamics of Iron Responsive Protein 1 with the Ferritin Light Chain Iron Responsive Element"